Hormônio natural do sono - Melatonina SR (Liberação Prolongada)

<p><span -webkit-text-stroke-width:="" background-color:="" color:="" display:="" float:="" font-feature-settings:="" font-kerning:="" font-optical-sizing:="" font-size-adjust:="" font-size:="" font-style:="" font-variant-caps:="" font-variant-ligatures:="" font-variation-settings:="" helvetica="" inline="" letter-spacing:="" orphans:="" style="box-sizing: inherit; -webkit-tap-highlight-color: transparent; margin: 0px; padding: 0px; border: 0px; font-variant-numeric: inherit; font-variant-east-asian: inherit; font-variant-alternates: inherit; font-variant-position: inherit; font-variant-emoji: inherit; font-stretch: inherit; line-height: 1.5; font-family: roboto, Roboto, -apple-system, " text-align:="" text-decoration-color:="" text-decoration-style:="" text-decoration-thickness:="" text-indent:="" text-transform:="" vertical-align:="" white-space:="" widows:="" word-spacing:="">POSOLOGIA: Tomar uma c&aacute;psula &agrave; noite.</span></p> <div -webkit-text-stroke-width:="" 0.3s="" 0s="" 1="" animation:="" background-color:="" both="" color:="" font-feature-settings:="" font-kerning:="" font-optical-sizing:="" font-size-adjust:="" font-size:="" font-style:="" font-variant-caps:="" font-variant-ligatures:="" font-variation-settings:="" helvetica="" letter-spacing:="" normal="" orphans:="" running="" style="box-sizing: inherit; -webkit-tap-highlight-color: transparent; margin: 0px; padding: 0px; border: 0px; font-variant-numeric: inherit; font-variant-east-asian: inherit; font-variant-alternates: inherit; font-variant-position: inherit; font-variant-emoji: inherit; font-stretch: inherit; line-height: 1.5; font-family: roboto, Roboto, -apple-system, " text-align:="" text-decoration-color:="" text-decoration-style:="" text-decoration-thickness:="" text-indent:="" text-transform:="" vertical-align:="" white-space:="" widows:="" word-spacing:="">&nbsp;</div> <div -webkit-text-stroke-width:="" 0.3s="" 0s="" 1="" animation:="" background-color:="" both="" color:="" font-feature-settings:="" font-kerning:="" font-optical-sizing:="" font-size-adjust:="" font-size:="" font-style:="" font-variant-caps:="" font-variant-ligatures:="" font-variation-settings:="" helvetica="" letter-spacing:="" normal="" orphans:="" running="" style="box-sizing: inherit; -webkit-tap-highlight-color: transparent; margin: 0px; padding: 0px; border: 0px; font-variant-numeric: inherit; font-variant-east-asian: inherit; font-variant-alternates: inherit; font-variant-position: inherit; font-variant-emoji: inherit; font-stretch: inherit; line-height: 1.5; font-family: roboto, Roboto, -apple-system, " text-align:="" text-decoration-color:="" text-decoration-style:="" text-decoration-thickness:="" text-indent:="" text-transform:="" vertical-align:="" white-space:="" widows:="" word-spacing:=""><span style="font-size:16px;"><strong>Melatonina SR -LIBERA&Ccedil;&Atilde;O PROLONGADA</strong></span> - Apresenta uma libera&ccedil;&atilde;o gradual da melatonina no organismo, permitindo que o efeito seja durante as oito horas ideais de sono, evitando despertares noturnos.&nbsp; A Melatonina &eacute; um horm&ocirc;nio, e tem a fun&ccedil;&atilde;o de regular o metabolismo e os ritmos biol&oacute;gicos do organismo, atuando principalmente no ciclo vig&iacute;lia-sono, no sistema imunol&oacute;gico, cardiovascular (press&atilde;o arterial), estado de humor, balan&ccedil;o energ&eacute;tico e no controle das atividades sexuais e de reprodu&ccedil;&atilde;o.</div> <div -webkit-text-stroke-width:="" 0.3s="" 0s="" 1="" animation:="" background-color:="" both="" color:="" font-feature-settings:="" font-kerning:="" font-optical-sizing:="" font-size-adjust:="" font-size:="" font-style:="" font-variant-caps:="" font-variant-ligatures:="" font-variation-settings:="" helvetica="" letter-spacing:="" normal="" orphans:="" running="" style="box-sizing: inherit; -webkit-tap-highlight-color: transparent; margin: 0px; padding: 0px; border: 0px; font-variant-numeric: inherit; font-variant-east-asian: inherit; font-variant-alternates: inherit; font-variant-position: inherit; font-variant-emoji: inherit; font-stretch: inherit; line-height: 1.5; font-family: roboto, Roboto, -apple-system, " text-align:="" text-decoration-color:="" text-decoration-style:="" text-decoration-thickness:="" text-indent:="" text-transform:="" vertical-align:="" white-space:="" widows:="" word-spacing:="">&nbsp;</div> <div -webkit-text-stroke-width:="" 0.3s="" 0s="" 1="" animation:="" background-color:="" both="" color:="" font-feature-settings:="" font-kerning:="" font-optical-sizing:="" font-size-adjust:="" font-size:="" font-style:="" font-variant-caps:="" font-variant-ligatures:="" font-variation-settings:="" helvetica="" letter-spacing:="" normal="" orphans:="" running="" style="box-sizing: inherit; -webkit-tap-highlight-color: transparent; margin: 0px; padding: 0px; border: 0px; font-variant-numeric: inherit; font-variant-east-asian: inherit; font-variant-alternates: inherit; font-variant-position: inherit; font-variant-emoji: inherit; font-stretch: inherit; line-height: 1.5; font-family: roboto, Roboto, -apple-system, " text-align:="" text-decoration-color:="" text-decoration-style:="" text-decoration-thickness:="" text-indent:="" text-transform:="" vertical-align:="" white-space:="" widows:="" word-spacing:="">Fisiologicamente, a s&iacute;ntese end&oacute;gena de melatonina reduz com o avan&ccedil;o da idade, al&eacute;m disso, fatores externos (como ilumina&ccedil;&atilde;o durante o per&iacute;odo noturno) e algumas doen&ccedil;as tamb&eacute;m podem comprometer a s&iacute;ntese e a libera&ccedil;&atilde;o de melatonina pela <a href="https://pt.wikipedia.org/wiki/Gl%C3%A2ndula_pineal" target="_blank">gl&acirc;ndula pineal</a>.</div> <div -webkit-text-stroke-width:="" 0.3s="" 0s="" 1="" animation:="" background-color:="" both="" color:="" font-feature-settings:="" font-kerning:="" font-optical-sizing:="" font-size-adjust:="" font-size:="" font-style:="" font-variant-caps:="" font-variant-ligatures:="" font-variation-settings:="" helvetica="" letter-spacing:="" normal="" orphans:="" running="" style="box-sizing: inherit; -webkit-tap-highlight-color: transparent; margin: 0px; padding: 0px; border: 0px; font-variant-numeric: inherit; font-variant-east-asian: inherit; font-variant-alternates: inherit; font-variant-position: inherit; font-variant-emoji: inherit; font-stretch: inherit; line-height: 1.5; font-family: roboto, Roboto, -apple-system, " text-align:="" text-decoration-color:="" text-decoration-style:="" text-decoration-thickness:="" text-indent:="" text-transform:="" vertical-align:="" white-space:="" widows:="" word-spacing:="">&nbsp;</div> <div -webkit-text-stroke-width:="" 0.3s="" 0s="" 1="" animation:="" background-color:="" both="" color:="" font-feature-settings:="" font-kerning:="" font-optical-sizing:="" font-size-adjust:="" font-size:="" font-style:="" font-variant-caps:="" font-variant-ligatures:="" font-variation-settings:="" helvetica="" letter-spacing:="" normal="" orphans:="" running="" style="box-sizing: inherit; -webkit-tap-highlight-color: transparent; margin: 0px; padding: 0px; border: 0px; font-variant-numeric: inherit; font-variant-east-asian: inherit; font-variant-alternates: inherit; font-variant-position: inherit; font-variant-emoji: inherit; font-stretch: inherit; line-height: 1.5; font-family: roboto, Roboto, -apple-system, " text-align:="" text-decoration-color:="" text-decoration-style:="" text-decoration-thickness:="" text-indent:="" text-transform:="" vertical-align:="" white-space:="" widows:="" word-spacing:="">Nestas condi&ccedil;&otilde;es, o tratamento com melatonina vem sendo utilizado visando restaurar as fun&ccedil;&otilde;es fisiol&oacute;gicas necess&aacute;rias para o funcionamento adequado do organismo &ndash; sobretudo para promover a melhora da qualidade do sono.</div> <div -webkit-text-stroke-width:="" 0.3s="" 0s="" 1="" animation:="" background-color:="" both="" color:="" font-feature-settings:="" font-kerning:="" font-optical-sizing:="" font-size-adjust:="" font-size:="" font-style:="" font-variant-caps:="" font-variant-ligatures:="" font-variation-settings:="" helvetica="" letter-spacing:="" normal="" orphans:="" running="" style="box-sizing: inherit; -webkit-tap-highlight-color: transparent; margin: 0px; padding: 0px; border: 0px; font-variant-numeric: inherit; font-variant-east-asian: inherit; font-variant-alternates: inherit; font-variant-position: inherit; font-variant-emoji: inherit; font-stretch: inherit; line-height: 1.5; font-family: roboto, Roboto, -apple-system, " text-align:="" text-decoration-color:="" text-decoration-style:="" text-decoration-thickness:="" text-indent:="" text-transform:="" vertical-align:="" white-space:="" widows:="" word-spacing:="">&nbsp;</div> <div -webkit-text-stroke-width:="" 0.3s="" 0s="" 1="" animation:="" background-color:="" both="" color:="" font-feature-settings:="" font-kerning:="" font-optical-sizing:="" font-size-adjust:="" font-size:="" font-style:="" font-variant-caps:="" font-variant-ligatures:="" font-variation-settings:="" helvetica="" letter-spacing:="" normal="" orphans:="" running="" style="box-sizing: inherit; -webkit-tap-highlight-color: transparent; margin: 0px; padding: 0px; border: 0px; font-variant-numeric: inherit; font-variant-east-asian: inherit; font-variant-alternates: inherit; font-variant-position: inherit; font-variant-emoji: inherit; font-stretch: inherit; line-height: 1.5; font-family: roboto, Roboto, -apple-system, " text-align:="" text-decoration-color:="" text-decoration-style:="" text-decoration-thickness:="" text-indent:="" text-transform:="" vertical-align:="" white-space:="" widows:="" word-spacing:="">Entretanto, ap&oacute;s administra&ccedil;&atilde;o pela via oral, a melatonina &eacute; rapidamente absorvida pelo epit&eacute;lio intestinal e metabolizada no f&iacute;gado, o que limita a sua biodisponibilidade no sistema nervoso central (SNC). Com isso, o tempo de a&ccedil;&atilde;o da melatonina pode ser reduzido, levando ao despertar precoce em alguns indiv&iacute;duos.</div> <div -webkit-text-stroke-width:="" 0.3s="" 0s="" 1="" animation:="" background-color:="" both="" color:="" font-feature-settings:="" font-kerning:="" font-optical-sizing:="" font-size-adjust:="" font-size:="" font-style:="" font-variant-caps:="" font-variant-ligatures:="" font-variation-settings:="" helvetica="" letter-spacing:="" normal="" orphans:="" running="" style="box-sizing: inherit; -webkit-tap-highlight-color: transparent; margin: 0px; padding: 0px; border: 0px; font-variant-numeric: inherit; font-variant-east-asian: inherit; font-variant-alternates: inherit; font-variant-position: inherit; font-variant-emoji: inherit; font-stretch: inherit; line-height: 1.5; font-family: roboto, Roboto, -apple-system, " text-align:="" text-decoration-color:="" text-decoration-style:="" text-decoration-thickness:="" text-indent:="" text-transform:="" vertical-align:="" white-space:="" widows:="" word-spacing:="">&nbsp;</div> <div -webkit-text-stroke-width:="" 0.3s="" 0s="" 1="" animation:="" background-color:="" both="" color:="" font-feature-settings:="" font-kerning:="" font-optical-sizing:="" font-size-adjust:="" font-size:="" font-style:="" font-variant-caps:="" font-variant-ligatures:="" font-variation-settings:="" helvetica="" letter-spacing:="" normal="" orphans:="" running="" style="box-sizing: inherit; -webkit-tap-highlight-color: transparent; margin: 0px; padding: 0px; border: 0px; font-variant-numeric: inherit; font-variant-east-asian: inherit; font-variant-alternates: inherit; font-variant-position: inherit; font-variant-emoji: inherit; font-stretch: inherit; line-height: 1.5; font-family: roboto, Roboto, -apple-system, " text-align:="" text-decoration-color:="" text-decoration-style:="" text-decoration-thickness:="" text-indent:="" text-transform:="" vertical-align:="" white-space:="" widows:="" word-spacing:="">Neste contexto, a Melatonina SR (do ingl&ecirc;s, &ldquo;slow release&rdquo; ou &ldquo;sustained release&rdquo;) &eacute; um insumo com tecnologia exclusiva que permite um perfil de libera&ccedil;&atilde;o gradual da melatonina no organismo, apresentando maior biodisponibilidade do que a forma convencional.</div> <div -webkit-text-stroke-width:="" 0.3s="" 0s="" 1="" animation:="" background-color:="" both="" color:="" font-feature-settings:="" font-kerning:="" font-optical-sizing:="" font-size-adjust:="" font-size:="" font-style:="" font-variant-caps:="" font-variant-ligatures:="" font-variation-settings:="" helvetica="" letter-spacing:="" normal="" orphans:="" running="" style="box-sizing: inherit; -webkit-tap-highlight-color: transparent; margin: 0px; padding: 0px; border: 0px; font-variant-numeric: inherit; font-variant-east-asian: inherit; font-variant-alternates: inherit; font-variant-position: inherit; font-variant-emoji: inherit; font-stretch: inherit; line-height: 1.5; font-family: roboto, Roboto, -apple-system, " text-align:="" text-decoration-color:="" text-decoration-style:="" text-decoration-thickness:="" text-indent:="" text-transform:="" vertical-align:="" white-space:="" widows:="" word-spacing:="">&nbsp;</div> <div -webkit-text-stroke-width:="" 0.3s="" 0s="" 1="" animation:="" background-color:="" both="" color:="" font-feature-settings:="" font-kerning:="" font-optical-sizing:="" font-size-adjust:="" font-size:="" font-style:="" font-variant-caps:="" font-variant-ligatures:="" font-variation-settings:="" helvetica="" letter-spacing:="" normal="" orphans:="" running="" style="box-sizing: inherit; -webkit-tap-highlight-color: transparent; margin: 0px; padding: 0px; border: 0px; font-variant-numeric: inherit; font-variant-east-asian: inherit; font-variant-alternates: inherit; font-variant-position: inherit; font-variant-emoji: inherit; font-stretch: inherit; line-height: 1.5; font-family: roboto, Roboto, -apple-system, " text-align:="" text-decoration-color:="" text-decoration-style:="" text-decoration-thickness:="" text-indent:="" text-transform:="" vertical-align:="" white-space:="" widows:="" word-spacing:="">Seu diferencial est&aacute; no fato de que, al&eacute;m de auxiliar na indu&ccedil;&atilde;o do sono, o perfil de libera&ccedil;&atilde;o modificado favorece a manuten&ccedil;&atilde;o do sono, evitando os despertares noturnos, a melhora da qualidade do sono e pode auxiliar no manejo de quadros de ins&ocirc;nia.</div>