Melatonina SR (Liberação Prolongada)

<p><span -webkit-text-stroke-width:="" background-color:="" color:="" display:="" float:="" font-feature-settings:="" font-kerning:="" font-optical-sizing:="" font-size-adjust:="" font-size:="" font-style:="" font-variant-caps:="" font-variant-ligatures:="" font-variation-settings:="" helvetica="" inline="" letter-spacing:="" orphans:="" style="box-sizing: inherit; -webkit-tap-highlight-color: transparent; margin: 0px; padding: 0px; border: 0px; font-variant-numeric: inherit; font-variant-east-asian: inherit; font-variant-alternates: inherit; font-variant-position: inherit; font-variant-emoji: inherit; font-stretch: inherit; line-height: 1.5; font-family: roboto, Roboto, -apple-system, " text-align:="" text-decoration-color:="" text-decoration-style:="" text-decoration-thickness:="" text-indent:="" text-transform:="" vertical-align:="" white-space:="" widows:="" word-spacing:="">POSOLOGIA: Tomar uma cápsula à noite.</span></p> <div -webkit-text-stroke-width:="" 0.3s="" 0s="" 1="" animation:="" background-color:="" both="" color:="" font-feature-settings:="" font-kerning:="" font-optical-sizing:="" font-size-adjust:="" font-size:="" font-style:="" font-variant-caps:="" font-variant-ligatures:="" font-variation-settings:="" helvetica="" letter-spacing:="" normal="" orphans:="" running="" style="box-sizing: inherit; -webkit-tap-highlight-color: transparent; margin: 0px; padding: 0px; border: 0px; font-variant-numeric: inherit; font-variant-east-asian: inherit; font-variant-alternates: inherit; font-variant-position: inherit; font-variant-emoji: inherit; font-stretch: inherit; line-height: 1.5; font-family: roboto, Roboto, -apple-system, " text-align:="" text-decoration-color:="" text-decoration-style:="" text-decoration-thickness:="" text-indent:="" text-transform:="" vertical-align:="" white-space:="" widows:="" word-spacing:=""> </div> <div -webkit-text-stroke-width:="" 0.3s="" 0s="" 1="" animation:="" background-color:="" both="" color:="" font-feature-settings:="" font-kerning:="" font-optical-sizing:="" font-size-adjust:="" font-size:="" font-style:="" font-variant-caps:="" font-variant-ligatures:="" font-variation-settings:="" helvetica="" letter-spacing:="" normal="" orphans:="" running="" style="box-sizing: inherit; -webkit-tap-highlight-color: transparent; margin: 0px; padding: 0px; border: 0px; font-variant-numeric: inherit; font-variant-east-asian: inherit; font-variant-alternates: inherit; font-variant-position: inherit; font-variant-emoji: inherit; font-stretch: inherit; line-height: 1.5; font-family: roboto, Roboto, -apple-system, " text-align:="" text-decoration-color:="" text-decoration-style:="" text-decoration-thickness:="" text-indent:="" text-transform:="" vertical-align:="" white-space:="" widows:="" word-spacing:=""><span style="font-size:16px;"><strong>Melatonina SR -LIBERAÇÃO PROLONGADA</strong></span> - Apresenta uma liberação gradual da melatonina no organismo, permitindo que o efeito seja durante as oito horas ideais de sono, evitando despertares noturnos.  A Melatonina é um hormônio, e tem a função de regular o metabolismo e os ritmos biológicos do organismo, atuando principalmente no ciclo vigília-sono, no sistema imunológico, cardiovascular (pressão arterial), estado de humor, balanço energético e no controle das atividades sexuais e de reprodução.</div> <div -webkit-text-stroke-width:="" 0.3s="" 0s="" 1="" animation:="" background-color:="" both="" color:="" font-feature-settings:="" font-kerning:="" font-optical-sizing:="" font-size-adjust:="" font-size:="" font-style:="" font-variant-caps:="" font-variant-ligatures:="" font-variation-settings:="" helvetica="" letter-spacing:="" normal="" orphans:="" running="" style="box-sizing: inherit; -webkit-tap-highlight-color: transparent; margin: 0px; padding: 0px; border: 0px; font-variant-numeric: inherit; font-variant-east-asian: inherit; font-variant-alternates: inherit; font-variant-position: inherit; font-variant-emoji: inherit; font-stretch: inherit; line-height: 1.5; font-family: roboto, Roboto, -apple-system, " text-align:="" text-decoration-color:="" text-decoration-style:="" text-decoration-thickness:="" text-indent:="" text-transform:="" vertical-align:="" white-space:="" widows:="" word-spacing:=""> </div> <div -webkit-text-stroke-width:="" 0.3s="" 0s="" 1="" animation:="" background-color:="" both="" color:="" font-feature-settings:="" font-kerning:="" font-optical-sizing:="" font-size-adjust:="" font-size:="" font-style:="" font-variant-caps:="" font-variant-ligatures:="" font-variation-settings:="" helvetica="" letter-spacing:="" normal="" orphans:="" running="" style="box-sizing: inherit; -webkit-tap-highlight-color: transparent; margin: 0px; padding: 0px; border: 0px; font-variant-numeric: inherit; font-variant-east-asian: inherit; font-variant-alternates: inherit; font-variant-position: inherit; font-variant-emoji: inherit; font-stretch: inherit; line-height: 1.5; font-family: roboto, Roboto, -apple-system, " text-align:="" text-decoration-color:="" text-decoration-style:="" text-decoration-thickness:="" text-indent:="" text-transform:="" vertical-align:="" white-space:="" widows:="" word-spacing:="">Fisiologicamente, a síntese endógena de melatonina reduz com o avanço da idade, além disso, fatores externos (como iluminação durante o período noturno) e algumas doenças também podem comprometer a síntese e a liberação de melatonina pela glândula pineal.</div> <div -webkit-text-stroke-width:="" 0.3s="" 0s="" 1="" animation:="" background-color:="" both="" color:="" font-feature-settings:="" font-kerning:="" font-optical-sizing:="" font-size-adjust:="" font-size:="" font-style:="" font-variant-caps:="" font-variant-ligatures:="" font-variation-settings:="" helvetica="" letter-spacing:="" normal="" orphans:="" running="" style="box-sizing: inherit; -webkit-tap-highlight-color: transparent; margin: 0px; padding: 0px; border: 0px; font-variant-numeric: inherit; font-variant-east-asian: inherit; font-variant-alternates: inherit; font-variant-position: inherit; font-variant-emoji: inherit; font-stretch: inherit; line-height: 1.5; font-family: roboto, Roboto, -apple-system, " text-align:="" text-decoration-color:="" text-decoration-style:="" text-decoration-thickness:="" text-indent:="" text-transform:="" vertical-align:="" white-space:="" widows:="" word-spacing:=""> </div> <div -webkit-text-stroke-width:="" 0.3s="" 0s="" 1="" animation:="" background-color:="" both="" color:="" font-feature-settings:="" font-kerning:="" font-optical-sizing:="" font-size-adjust:="" font-size:="" font-style:="" font-variant-caps:="" font-variant-ligatures:="" font-variation-settings:="" helvetica="" letter-spacing:="" normal="" orphans:="" running="" style="box-sizing: inherit; -webkit-tap-highlight-color: transparent; margin: 0px; padding: 0px; border: 0px; font-variant-numeric: inherit; font-variant-east-asian: inherit; font-variant-alternates: inherit; font-variant-position: inherit; font-variant-emoji: inherit; font-stretch: inherit; line-height: 1.5; font-family: roboto, Roboto, -apple-system, " text-align:="" text-decoration-color:="" text-decoration-style:="" text-decoration-thickness:="" text-indent:="" text-transform:="" vertical-align:="" white-space:="" widows:="" word-spacing:="">Nestas condições, o tratamento com melatonina vem sendo utilizado visando restaurar as funções fisiológicas necessárias para o funcionamento adequado do organismo &ndash; sobretudo para promover a melhora da qualidade do sono.</div> <div -webkit-text-stroke-width:="" 0.3s="" 0s="" 1="" animation:="" background-color:="" both="" color:="" font-feature-settings:="" font-kerning:="" font-optical-sizing:="" font-size-adjust:="" font-size:="" font-style:="" font-variant-caps:="" font-variant-ligatures:="" font-variation-settings:="" helvetica="" letter-spacing:="" normal="" orphans:="" running="" style="box-sizing: inherit; -webkit-tap-highlight-color: transparent; margin: 0px; padding: 0px; border: 0px; font-variant-numeric: inherit; font-variant-east-asian: inherit; font-variant-alternates: inherit; font-variant-position: inherit; font-variant-emoji: inherit; font-stretch: inherit; line-height: 1.5; font-family: roboto, Roboto, -apple-system, " text-align:="" text-decoration-color:="" text-decoration-style:="" text-decoration-thickness:="" text-indent:="" text-transform:="" vertical-align:="" white-space:="" widows:="" word-spacing:=""> </div> <div -webkit-text-stroke-width:="" 0.3s="" 0s="" 1="" animation:="" background-color:="" both="" color:="" font-feature-settings:="" font-kerning:="" font-optical-sizing:="" font-size-adjust:="" font-size:="" font-style:="" font-variant-caps:="" font-variant-ligatures:="" font-variation-settings:="" helvetica="" letter-spacing:="" normal="" orphans:="" running="" style="box-sizing: inherit; -webkit-tap-highlight-color: transparent; margin: 0px; padding: 0px; border: 0px; font-variant-numeric: inherit; font-variant-east-asian: inherit; font-variant-alternates: inherit; font-variant-position: inherit; font-variant-emoji: inherit; font-stretch: inherit; line-height: 1.5; font-family: roboto, Roboto, -apple-system, " text-align:="" text-decoration-color:="" text-decoration-style:="" text-decoration-thickness:="" text-indent:="" text-transform:="" vertical-align:="" white-space:="" widows:="" word-spacing:="">Entretanto, após administração pela via oral, a melatonina é rapidamente absorvida pelo epitélio intestinal e metabolizada no fígado, o que limita a sua biodisponibilidade no sistema nervoso central (SNC). Com isso, o tempo de ação da melatonina pode ser reduzido, levando ao despertar precoce em alguns indivíduos.</div> <div -webkit-text-stroke-width:="" 0.3s="" 0s="" 1="" animation:="" background-color:="" both="" color:="" font-feature-settings:="" font-kerning:="" font-optical-sizing:="" font-size-adjust:="" font-size:="" font-style:="" font-variant-caps:="" font-variant-ligatures:="" font-variation-settings:="" helvetica="" letter-spacing:="" normal="" orphans:="" running="" style="box-sizing: inherit; -webkit-tap-highlight-color: transparent; margin: 0px; padding: 0px; border: 0px; font-variant-numeric: inherit; font-variant-east-asian: inherit; font-variant-alternates: inherit; font-variant-position: inherit; font-variant-emoji: inherit; font-stretch: inherit; line-height: 1.5; font-family: roboto, Roboto, -apple-system, " text-align:="" text-decoration-color:="" text-decoration-style:="" text-decoration-thickness:="" text-indent:="" text-transform:="" vertical-align:="" white-space:="" widows:="" word-spacing:=""> </div> <div -webkit-text-stroke-width:="" 0.3s="" 0s="" 1="" animation:="" background-color:="" both="" color:="" font-feature-settings:="" font-kerning:="" font-optical-sizing:="" font-size-adjust:="" font-size:="" font-style:="" font-variant-caps:="" font-variant-ligatures:="" font-variation-settings:="" helvetica="" letter-spacing:="" normal="" orphans:="" running="" style="box-sizing: inherit; -webkit-tap-highlight-color: transparent; margin: 0px; padding: 0px; border: 0px; font-variant-numeric: inherit; font-variant-east-asian: inherit; font-variant-alternates: inherit; font-variant-position: inherit; font-variant-emoji: inherit; font-stretch: inherit; line-height: 1.5; font-family: roboto, Roboto, -apple-system, " text-align:="" text-decoration-color:="" text-decoration-style:="" text-decoration-thickness:="" text-indent:="" text-transform:="" vertical-align:="" white-space:="" widows:="" word-spacing:="">Neste contexto, a Melatonina SR (do inglês, &ldquo;slow release&rdquo; ou &ldquo;sustained release&rdquo;) é um insumo com tecnologia exclusiva que permite um perfil de liberação gradual da melatonina no organismo, apresentando maior biodisponibilidade do que a forma convencional.</div> <div -webkit-text-stroke-width:="" 0.3s="" 0s="" 1="" animation:="" background-color:="" both="" color:="" font-feature-settings:="" font-kerning:="" font-optical-sizing:="" font-size-adjust:="" font-size:="" font-style:="" font-variant-caps:="" font-variant-ligatures:="" font-variation-settings:="" helvetica="" letter-spacing:="" normal="" orphans:="" running="" style="box-sizing: inherit; -webkit-tap-highlight-color: transparent; margin: 0px; padding: 0px; border: 0px; font-variant-numeric: inherit; font-variant-east-asian: inherit; font-variant-alternates: inherit; font-variant-position: inherit; font-variant-emoji: inherit; font-stretch: inherit; line-height: 1.5; font-family: roboto, Roboto, -apple-system, " text-align:="" text-decoration-color:="" text-decoration-style:="" text-decoration-thickness:="" text-indent:="" text-transform:="" vertical-align:="" white-space:="" widows:="" word-spacing:=""> </div> <div -webkit-text-stroke-width:="" 0.3s="" 0s="" 1="" animation:="" background-color:="" both="" color:="" font-feature-settings:="" font-kerning:="" font-optical-sizing:="" font-size-adjust:="" font-size:="" font-style:="" font-variant-caps:="" font-variant-ligatures:="" font-variation-settings:="" helvetica="" letter-spacing:="" normal="" orphans:="" running="" style="box-sizing: inherit; -webkit-tap-highlight-color: transparent; margin: 0px; padding: 0px; border: 0px; font-variant-numeric: inherit; font-variant-east-asian: inherit; font-variant-alternates: inherit; font-variant-position: inherit; font-variant-emoji: inherit; font-stretch: inherit; line-height: 1.5; font-family: roboto, Roboto, -apple-system, " text-align:="" text-decoration-color:="" text-decoration-style:="" text-decoration-thickness:="" text-indent:="" text-transform:="" vertical-align:="" white-space:="" widows:="" word-spacing:="">Seu diferencial está no fato de que, além de auxiliar na indução do sono, o perfil de liberação modificado favorece a manutenção do sono, evitando os despertares noturnos, a melhora da qualidade do sono e pode auxiliar no manejo de quadros de insônia.</div>